AHA Postdoctoral Fellow

Allison  Brackley

AHA Postdoctoral Fellow

Cellular & Integrative Physiology

Mentor:  Glenn M. Toney

Phone:  (210) 421-6416

Email:  brackleya@uthscsa.edu

ORCID iD:  https://orcid.org/0000-0002-9552-3159

Education

2010 BS in Biochemistry; BS in Nutrition; Minor in General Science Texas Woman's University
2017 PhD in Pharmacology; Neuroscience Track University of Texas Health Science Center

Honors

2012 2nd Place Student Poster Presentation Award; 10th Annual Center for Biomedical Neuroscience (CBN) Retreat
2013-2015 T32 NRSA Institutional Fellowship; Craniofacial Oral-Biology Student Training in Academic Research (COSTAR) Predoctoral Fellowship
2014-2015 Co-leader of COSTAR Planning Committee; Craniofacial Oral-Biology Student Training in Academic Research (COSTAR) Predoctoral Fellowship
2015-2017 F31 NRSA Individual Fellowship; Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31 – Diversity)
2015 1st Place Outstanding Graduate Student Poster; 22nd Annual Graduate Student Symposium
2016 American Society for Biochemistry & Molecular Biology 2016 Graduate/Postdoctoral Travel Award
2016 1st Place Student Poster Presentation Award; 14th Annual Center for Biomedical Neuroscience (CBN) Retreat
2016 American Pain Society Young Investigator Travel Award
2017 Honorarium CME Opioid Ethics Lecturer; Baptist Health System Ethics Checkup 2017 Symposium
2017 NIH Invited & Sponsored Poster Presenter; 12th Annual Symposium on Advances in Pain Research

Publications

  1. Brackley AD & Toney GM (2021) Oxytocin receptor activation rescues opioid-induced respiratory depression by systemic fentanyl in the rat. Under Review.
  2. Brackley AD, Flores EF, Gomez R, Guerrero KA, Jeske NA (2021) FDA-approved drug enhances delta opioid receptor competence in peripheral sensory neurons. Under Review.
  3. Brackley AD, Andrade MA, Toney GM (2020) Intermittent hypercapnic hypoxia induces respiratory hypersensitivity to fentanyl accompanied by tonic respiratory depression by endogenous opioids. J Physiol Online ahead of print (PMID:32415789)
  4. Gomez R, Kohler DM, Brackley AD, Henry MA, Jeske NA (2018) Serum response factor mediates nociceptor inflammatory pain plasticity. Pain Rep 3(3):e658 (PMID29922747:PMC5999410)
  5. Por ED, Sandoval ML, Thomas-Benson C, Burke TA, Doyle Brackley A, Jeske NA, Cleland JM, Lund BJ (2017) Repeat low-level blast exposure increases transient receptor potential vanilloid (TRPV1) and endothelin-1 (ET-1) expression in the trigeminal ganglion. PLoS One 12(8):e0182102 (PMID28797041:PMC5552217)
  6. Brackley AD, Gomez R, Guerrero KA, Akopian AN, Du J, Carlton SM, Jeske NA (2017) A-Kinase Anchoring Protein 79/150 Scaffolds Transient Receptor Potential A 1 Phosphorylation and Sensitization by Metabotropic Glutamate Receptor Activation. Scientific Reports 7 (1): 1842 (PMID 28500286:PMC5431798)
  7. Brackley AD, Sarrami S, Gomez R, Guerrero KA, Jeske NA (2017) Identification of a signaling cascade that maintains constitutive delta opioid receptor incompetence in peripheral sensory neurons. J Biol Chem 292(21):8762-8772 (PMID 28381559:PMC5448103)
  8. Brackley AD, Gomez R, Akopian AN, Henry MA, Jeske NA (2016) GRK2 constitutively desensitizes delta opioid receptor in the periphery. Cell Reports 16(10):2686-98 (PMID27568556:PMC5014669)
  9. Hallums DP, Gomez R, Doyle AP, Viet C, Schmidt BL, Jeske NA (2016) RKIP in expression and phosphorylation in oral cancer. Clin Surg 1:1100 (PMID28529999:PMC5436720)
  10. Rowan MP, Szteyn K, Doyle AP, Gomez R, Henry MA, Jeske NA (2014) β-arrestin-2-biased agonism of delta opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) in primary sensory neurons. Molecular Pain 10:50 (PMID:PMC4131480)