Post Doctoral Research Fellow

Miguel (Mike)  de la Flor

Post Doctoral Research Fellow

Cell Systems and Anatomy

Mentor:  Dr. Erzsebet Kokovay

Email:  delaflor@uthscsa.edu

Dr. Miguel de la Flor, PhD

 

 

Education

2019 PhD University of Houston

Research

How neurons control behaviors is a major research interest for me. Specifically, I am interested in investigating the molecular and cellular mechanisms involved in cognition such as learning and memory, decision-making and perception.

In my PhD career at the University of Houston I characterized the role of serotonergic (5-HT) signaling in novelty habituation, a form or learning and memory, in the Drosophila brain. My findings from pharmacological and transgenic (including circuit-breaking optogenetic and thermogenetic) experiments identified distinct 5-HT secreting neurons that may modulate specialized circuits that regulate habituation to novelty.

I am also interested in the translation of basic science research to novel clinical applications and therapies to mitigate the impact of neurodegenerative diseases. As a result, in the lab of Dr. Kokovay at UTHSCSA I investigate the molecular and cellular mechanisms that may, in an age-dependent manner,  regulate neurogeneis in the mouse ventricular-subventricular zone and hippocampus.

Professional Memberships

Board Certified Medical Illustrator Association of Medical Illustrators

Publications

  1. de la Flor M, Zhang S, Chen L, Gunaratne G, Dauwalder B, Garcia S, Wang M, Roman G. (2020) A dorsal paired medial neuron-mushroom body circuit that modulates habituation during exploration in Drosophila. Manuscript in preliminary preparation.
     
  2. Wayne C and de la Flor M. (2020).Unraveling the Epididymis: A Review of Its Structure and Function. HAPS Educator 24(1):562-69.
     
  3. de la Flor M, Chen L, Manson-Bishop C, Chu T-C, Zamora K, Robbins D, Gunarante G, Roman G.  (2017) Drosophila increase exploration after visually detecting predators. PLoS ONE 12(7): e0180749.