Postdoctoral Fellow

Rui  Hua

Postdoctoral Fellow

Biochemistry and Structural Biology

Mentor:  Dr. Jean X. Jiang

Phone:  2105624077

Email:  huar@uthscsa.edu

Research Mentor's Lab

Education

2016 Ph.D. Peking University
2010 B.S. Beijing Normal University

Honors

2020 ICMRS Webster Jee Young Investigator Award
2019 ASBMR Young Investigator Travel Grant

Professional Memberships

2017-2020 American Society for Bone and Mineral Research
2017-2020 International Chinese Musculoskeletal Research Society

Publications

  1. Hua R.*, Wei M.P.* and Zhang C. (2015). The complex genetics in autism spectrum disorders. Science China Life Sciences 58:933-945.
  2. Jiang W.*, Hua R.*, Wei M.P.*, Li C.H., Qiu Z.L., Yang X.F. and Zhang C. (2015). An optimized method for high-titer lentivirus preparations without ultracentrifugation. Scientific reports 5: 13875.
  3. Meng Y.*, Li H.Y.*, Hua R.*, Wang H.L., Lu J., Yu X. and Zhang C. (2015). A correlativity study of plasma APL1β28 and clusterin levels with MMSE/MoCA/CASI in aMCI patients. Scientific reports 5: 15546.
  4. Shen C.*, Rathore S.*, Yu H.J.*, Gulbranson D., Hua R., Zhang C., Schoppa N. and Shen J.S. (2015). The trans-SNARE-regulating function of Munc18-1 is essential to synaptic exocytosis. Nature Communications 6: 8852.
  5. Xie R.*, Dong L.*, Du Y.F., Zhu Y.T., Hua R., Zhang C. and Chen X. (2016). In vivo metabolic labeling of sialoglycans in the mouse brain. Proc Natl Acad Sci USA 113: 5173-5178.
  6. Wang X., Hua R., Ahsan A., Ni Q., Huang Y., Gu S., and Jiang J.X. (2018). Age-related deterioration of bone toughness is related to diminishing amount of matrix glycosaminoglycans (GAGs). J. Bone Miner. Res. Plus. 2(3): 164-173.
  7. Kar R.*, Riquelme M.A.*, Hua R. and Jiang J.X. (2018). Glucocorticoid‐Induced Autophagy Protects Osteocytes Against Oxidative Stress Through Activation of MAPK/ERK Signaling. J. Bone Miner. Res. Plus. 3(4): e10077.
  8. Ma L.*, Hua R.*, Tian Y., Cheng H., Fajardo R.J., Pearson J.J., Guda T., Shropshire D.B., Gu S. and Jiang J.X. (2019). Connexin 43 hemichannels protect bone loss during estrogen deficiency. Bone research, 7.
  9. Werner S.L., Sharma R., Woodruff K., Horn D., Harris S.E., Gorin Y., Lee D.Y., Hua R., Gu S., Fajardo R.J., Habib S.L. and Jiang J.X (2020). CSF‐1 in Osteocytes Inhibits Nox4‐mediated Oxidative Stress and Promotes Normal Bone Homeostasis. J. Bone Mineral Res. Plus. 4(7): e10080.
  10. Hua R.*, Ni Q., Eliason T.D., Han Y., Gu S., Nicolella D.P., Wang X. and Jiang J.X. (2020). Biglycan and chondroitin sulfate play pivotal roles in bone toughness via retaining bound water in bone mineral matrix. Matrix Biology. 94: 95-109.
  11. Riquelme M.A., Gu S., Hua R. and Jiang J.X. (2021). Mechanotransduction through coordinated actions of integrins, PI3K signaling and connexin hemichannels. Bone Research. 9(1): 1-11.
  12. Hua R.*, Zhang J.R., Riquelme M.A. and Jiang J.X. (2021). Connexin gap junctions and hemichannels link oxidative stress to skeletal physiology and pathology. Current Osteoporosis Reports. 1-9.