Postdoctoral Fellow

Simon  Leclerc

Postdoctoral Fellow

Molecular Medecine

Mentor:  Kitagawa Katsumi

Email:  leclerc@uthscsa.edu

Education

2018 Ph.D. Strasbourg (France)

Research

Microscopy! I did my Ph.D. thesis on single-molecule detection and quantification by using a highly-sensitive microscope. And before that, I got the opportunity to do some virology research in live microscopy - confocal and spinning disk.

Image analysis and feature extraction are also one of my interest, being able to automatize the analysis by programming is oddly satisfying.

Otherwise, developing new protocol for biology (molecular and cellular) is also one of my interest.

Publications

  1. Leclerc S, Arntz Y, Taniguchi Y. Extending single molecule imaging to proteome analysis by quantitation of fluorescent labeling homogeneity in complex sample. Bioconjugate Chemistry.2018. doi: 10.1021/acs.bioconjchem.8b00226. PubMed PMID: 29975043.
  2. Leclerc S, Arntz Y, Taniguchi Y. Proteome-wide quantification of labeling homogeneity at the single molecule level. Journal of Visualized Experiment. 2019. doi: 10.3791/59199. PubMed PMID: 31058902
  3. Kumar V., Leclerc S., Taniguchi Y., BHi-Cect: a top-down algorithm for identifying the multi-scale hierarchical structure of chromosomes, Nucleic Acids Research. 2020. doi: 10.1093/nar/gkaa004. PMID: 32009153