AHA Postdoctoral Fellow

Allison  Brackley

AHA Postdoctoral Fellow

Cellular & Integrative Physiology

Mentor:  Glenn M. Toney

Phone:  (210) 421-6416

Email:  brackleya@uthscsa.edu

ORCID iD:  https://orcid.org/0000-0002-9552-3159

Education

Honors

2017-2019 T32 NRSA Institutional Fellowship; Pathobiology of Occlusive Vascular Disease Postdoctoral Fellowship
2017 Texas Health & Human Services Commission Invited Speaker; Prescription Drug Misuse Prevention Town Hall
2017 Texas A&M University San Antonio Invited Speaker; Fall Learning Event “The Opioid Epidemic: A Dangerous Prescription for the Workplace”
2017 The Stephen B. Milam Memorial Scholarship; 2017 Pain Research Scholarship
2018 2018 American Physiological Society Research Recognition; 2018 Central Nervous System Section Research Recognition Award
2019 2019 American Physiological Society Data NCARnation Award Session; Neural Control and Autonomic Regulation Section of the American Physiological Society
2020-2021 American Heart Association Postdoctoral Fellowship; This award, Opioid-Induced Respiratory Depression: Unexpected Adaptations to the Hypothalamic Paraventricular Nucleus, is a two-year fellowship and received a score of 0.11%.
2021 2021 American Physiological Society Research Recognition; Neural Control and Autonomic Regulation Section of the American Physiological Society

Publications

  1. Brackley AD & Toney GM (2021) Oxytocin receptor activation rescues opioid-induced respiratory depression by systemic fentanyl in the rat. Under Review.
  2. Brackley AD, Flores EF, Gomez R, Guerrero KA, Jeske NA (2021) FDA-approved drug enhances delta opioid receptor competence in peripheral sensory neurons. Under Review.
  3. Brackley AD, Andrade MA, Toney GM (2020) Intermittent hypercapnic hypoxia induces respiratory hypersensitivity to fentanyl accompanied by tonic respiratory depression by endogenous opioids. J Physiol Online ahead of print (PMID:32415789)
  4. Gomez R, Kohler DM, Brackley AD, Henry MA, Jeske NA (2018) Serum response factor mediates nociceptor inflammatory pain plasticity. Pain Rep 3(3):e658 (PMID29922747:PMC5999410)
  5. Por ED, Sandoval ML, Thomas-Benson C, Burke TA, Doyle Brackley A, Jeske NA, Cleland JM, Lund BJ (2017) Repeat low-level blast exposure increases transient receptor potential vanilloid (TRPV1) and endothelin-1 (ET-1) expression in the trigeminal ganglion. PLoS One 12(8):e0182102 (PMID28797041:PMC5552217)
  6. Brackley AD, Gomez R, Guerrero KA, Akopian AN, Du J, Carlton SM, Jeske NA (2017) A-Kinase Anchoring Protein 79/150 Scaffolds Transient Receptor Potential A 1 Phosphorylation and Sensitization by Metabotropic Glutamate Receptor Activation. Scientific Reports 7 (1): 1842 (PMID 28500286:PMC5431798)
  7. Brackley AD, Sarrami S, Gomez R, Guerrero KA, Jeske NA (2017) Identification of a signaling cascade that maintains constitutive delta opioid receptor incompetence in peripheral sensory neurons. J Biol Chem 292(21):8762-8772 (PMID 28381559:PMC5448103)
  8. Brackley AD, Gomez R, Akopian AN, Henry MA, Jeske NA (2016) GRK2 constitutively desensitizes delta opioid receptor in the periphery. Cell Reports 16(10):2686-98 (PMID27568556:PMC5014669)
  9. Hallums DP, Gomez R, Doyle AP, Viet C, Schmidt BL, Jeske NA (2016) RKIP in expression and phosphorylation in oral cancer. Clin Surg 1:1100 (PMID28529999:PMC5436720)
  10. Rowan MP, Szteyn K, Doyle AP, Gomez R, Henry MA, Jeske NA (2014) β-arrestin-2-biased agonism of delta opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) in primary sensory neurons. Molecular Pain 10:50 (PMID:PMC4131480)