Postdoctoral Fellowship Position Available – DNA Damage Repair and Pediatric Sarcoma Therapy

Greehey Children’s Cancer Research Institute (GCCRI) at The University of Texas Health Science Center at San Antonio is seeking a Postdoctoral Fellow to work in the laboratory of Dr. Raushan Kurmasheva (http://gccri.uthscsa.edu/RKurmasheva.html). Research fellows will have the opportunity to interact with experts in basic and translational research at GCCRI.

Research will focus on understanding molecular basis of resistance to chemotherapeutics, and development of effective therapies for pediatric sarcomas. The laboratory studies DNA damage repair pathways involved in response to PARP inhibition, and utilizes the mouse sarcoma xenograft models to test novel drug combinations. There is in vitroand in vivo work to understand molecular mechanisms driving sensitivity/resistance to DNA damaging agents and DNA repair inhibitors. Project will include high-throughput studies to identifiy gene/drug targets, molecular characterization of protein interactions for drug discovery/development, and translational validation of basic discoveries in mouse models.