Office of Postdoctoral Affairs

Thangarajeswari Mohan

Postdoctoral Research Fellow

  • Professional Background

    Education

    • 2008-2011 - B.Sc., - Biochemistry - University of Madras
    • 2011-2013 - M.Sc., - Biochemistry - University of Madras
    • 2014-2022 - Ph.D., - University of Madras
  • Research

    Her research focuses on how aging impacts mammary epithelial cell identity and breast cancer susceptibility using in vivo mouse models. She studies age-related changes in stem-like cell behavior, luminal-to-basal plasticity, and oncogenic transformation, with a particular interest in the role of integrin α6 isoforms in mediating these processes.

  • Publications

    Mohan T, Narasimhan KKS, Ravi DB, Velusamy P, Chandrasekar N, Chakrapani LN, Srinivasan A, Karthikeyan P, Kannan P, Tamilarasan B, Johnson T, Kalaiselvan P, Periandavan K. Role of Nrf2 dysfunction in the pathogenesis of diabetic nephropathy: Therapeutic prospect of epigallocatechin-3-gallate. Free Radic Biol Med. 2020 Nov 20;160:227-238. 

    Mohan T, Velusamy P, Chakrapani LN, Srinivasan AK, Singh A, Johnson T, Periandavan K. Impact of EGCG Supplementation on the Progression of Diabetic Nephropathy in Rats: An Insight into Fibrosis and Apoptosis. J Agric Food Chem. 2017 Aug 30. PubMed PMID: 28823168.

    Mohan T, Periandavan K, Nayak D. Evaluation of hypolipidemic activity of homeopathic drug Allium sativum 6C potency on different grades of dyslipidemia in Wistar albino rat models. Phytomedicine Plus. 2022 Nov 1;2(4):100354.

    Mohan T, Rajkumar A, Panchalingam G, Nayak D, Raghunathan M, Periandavan K. Homeopathic preparation of Allium sativum abrogates OxLDL mediated atherogenic events in macrophages: An invitro and in silico approach. J Ayurveda Integr Med. 2024 Jan-Feb;15(1):100850. 

    Velusamy P, Mohan T, Ravi DB, Kishore Kumar SN, Srinivasan A, Chakrapani LN, Singh A, Varadharaj S, Kalaiselvi P. Targeting the Nrf2/ARE Signalling Pathway to Mitigate Isoproterenol-Induced Cardiac Hypertrophy: Plausible Role of Hesperetin in Redox Homeostasis. Oxid Med Cell Longev. 2020 Sep 1;2020:9568278.

    Narasimhan KKS, Jayakumar D, Velusamy P, Srinivasan A, Mohan T, Ravi DB, Uthamaraman S, Sathyamoorthy YK, Rajasekaran NS, Periandavan K. Morinda citrifolia and Its Active Principle Scopoletin Mitigate Protein Aggregation and Neuronal Apoptosis through Augmenting the DJ-1/Nrf2/ARE Signaling Pathway. Oxid Med Cell Longev. 2019 May 2;2019:2761041.

    Kannan P, Raghunathan M, Mohan T, Palanivelu S, Periandavan K. Gymnemic Acid Ameliorates Pancreatic β-Cell Dysfunction by Modulating Pdx1 Expression: A Possible Strategy for β-Cell Regeneration. Tissue Eng Regen Med. 2022 Feb 25. 

    Kannan P, Karthikeyan P, Subramaniam N, Mohan T, Gopinath B, Chakrapani LN, Palanivelu S, Raghunathan M, Periandavan K. Gymnemic acid protects murine pancreatic β-cells by moderating hyperglycemic stress-induced inflammation and apoptosis in type 1 diabetic rats. J Biochem Mol Toxicol. 2022 Mar 27:e23050. doi: 10.1002/jbt.23050. 

    Kishore Kumar SN, Deepthy J, Saraswathi U, Thangarajeswari M, Yogesh Kanna S, Ezhil P, Kalaiselvi P. Morinda citrifolia mitigates rotenone-induced striatal neuronal loss in male Sprague-Dawley rats by preventing mitochondrial pathway of intrinsic apoptosis. Redox Rep. 2016 Nov 24:1-12. 

    Karthikeyan P, Chakrapani LN, Mohan T, Tamilarasan B, Kannan P, Periandavan K. Gymnemic acid, a potent antidiabetic agent protects skeletal muscle from hyperglycemia mediated oxidative stress and apoptotic events in High fat and High fructose diet fed adult rats. ❖ Sumathi T, Shobana C, Thangarajeswari M, Usha R. Protective effect of L-Theanine against aluminium induced neurotoxicity in cerebral cortex, hippocampus and cerebellum of rat brain - histopathological, and biochemical approach. Drug Chem Toxicol. 2015 Jan;38(1):22-31.